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Levothyroxine

Levothyroxine

Levothyroxine is instrumental in treating hypothyroidism, a condition where the thyroid gland is underactive. Our thyroids produce hormones that help control our energy levels, our growth, and more.

Levothyroxine

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Uses

What Is Levothyroxine?

Levothyroxine is a synthetic form of the thyroid hormone, thyroxine (T4), which is produced by the thyroid gland. It is used to treat hypothyroidism, a condition in which the body does not produce enough thyroid hormone. Levothyroxine comes in tablet form and can be taken orally once a day.

What Is Levothyroxine Used For?

As mentioned earlier, levothyroxine is primarily used to treat hypothyroidism. This condition occurs when the thyroid gland does not produce enough T4 and other hormones needed for bodily functions. Without enough T4, individuals with this condition may experience symptoms such as fatigue, weight gain, hair loss, and depression.

In addition to treating hypothyroidism, levothyroxine is also used to prevent goiter, a condition in which the thyroid gland becomes enlarged due to insufficient hormone production. It may also be prescribed for certain types of thyroid cancer.

Furthermore, levothyroxine is sometimes used off-label to treat other conditions such as infertility, fibromyalgia, and high cholesterol levels. However, it should only be taken for these purposes under the supervision of a healthcare professional.

How Does Levothyroxine Work?

Levothyroxine works by replacing the deficient thyroid hormone in individuals with hypothyroidism. It is converted into an active form called triiodothyronine (T3) in the body, which helps regulate metabolism and other bodily functions. By restoring normal levels of thyroid hormone, levothyroxine can alleviate symptoms associated with hypothyroidism.

Levothyroxine Brand Names

  • Synthroid

  • Levoxyl

  • Tirosint

  • Unithroid

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Levothyroxine Side Effects

Common Side Effects

Like any medication, levothyroxine may cause side effects. Some of the most common ones include:

  • Headache

  • Nausea and vomiting

  • Stomach cramps

  • Diarrhea

  • Sweating

  • Insomnia

These side effects are usually mild and may go away as the body adjusts to the medication. If they persist or become severe, it is important to consult with a doctor.

Serious Side Effects

In rare cases, levothyroxine may cause more serious side effects that require immediate medical attention. These include:

  • Chest pain or rapid heartbeat (signs of a heart attack)

  • Severe headache or dizziness (signs of a stroke)

  • Difficulty breathing or swallowing

  • Allergic reaction (hives, rash, itching, swelling of the face or throat)

If you experience any of these symptoms while taking levothyroxine, seek medical help immediately.

Warnings

Levothyroxine may not be suitable for everyone. It is important to inform your doctor about any medical conditions you have and any other medications or supplements you are taking before starting levothyroxine.

Some important warnings to keep in mind when taking levothyroxine include:

Pregnancy

Pregnant or breastfeeding women should consult with their doctor before taking levothyroxine, as it can affect the health of both the mother and the baby.

Heart Conditions

People with certain heart conditions, such as angina, high blood pressure, or a history of heart attack, should use levothyroxine with caution.

Diabetes

Those with diabetes may need to adjust their dosage of insulin or other diabetes medications while taking levothyroxine.

Medications

Levothyroxine may interact with certain medications such as blood thinners, cholesterol-lowering drugs, and antidepressants. Always inform your doctor of all the medications you are taking to avoid potential interactions.

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Before Taking

Before starting levothyroxine, it is important to inform your doctor about any medical conditions you have, especially:

Heart Disease

People with heart disease may need to have their levothyroxine dosage adjusted.

Diabetes

Levothyroxine can affect blood sugar levels, so those with diabetes may need to monitor their glucose levels more closely while taking it.

Adrenal Gland Disorders

Those with adrenal gland disorders, such as Addison's disease, may need to take additional medication while taking levothyroxine.

Osteoporosis

Levothyroxine may increase the risk of osteoporosis in postmenopausal women. Your doctor may recommend calcium and vitamin D supplements to counteract this effect.

How to Take Levothyroxine

Levothyroxine should be taken exactly as prescribed by your doctor. It is usually taken once a day on an empty stomach, at least 30 minutes to an hour before breakfast. This allows for better absorption of the medication.

Regular Dosages

The typical starting dosage of levothyroxine for adults with hypothyroidism is 50-100 mcg per day. Dosages may be adjusted based on individual needs and blood test results.

Don't Chew the Tablet

Levothyroxine should be swallowed whole with a glass of water. Do not chew or crush the tablet as this may affect its absorption.

Missed Doses

If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take extra medication to make up for a missed dose.

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Dosages

For Adults

The typical dosage range for adults is 50-200 mcg per day, depending on individual needs and blood test results.

For Children

Children may require lower dosages of levothyroxine based on their weight. The usual starting dose for children is 12.5-50 mcg per day.

How Much Levothyroxine Can You Take?

The recommended dose of levothyroxine varies depending on the patient's age, weight, and the severity of their condition. Adults typically start with a daily dose of 50-100 micrograms, while children may start with a lower dose and gradually increase it over time.

It is important to take levothyroxine exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting with your doctor first.

What if I Miss a Dose of Levothyroxine?

If you forget to take a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

What if I Take Too Much Levothyroxine?

Taking too much levothyroxine can lead to symptoms of hyperthyroidism (an overactive thyroid). These may include:

  • Rapid or irregular heartbeat

  • Increased sweating

  • Mood swings

  • Weight loss

In case of an accidental overdose, seek medical help immediately.

How Long Does It Take Levothyroxine to Work?

It may take several weeks for levothyroxine to reach its full effect. Your doctor will monitor your progress through regular blood tests and make adjustments to your dosage as needed.

Can I Stop Taking Levothyroxine?

Levothyroxine is often taken for life, as stopping the medication can cause symptoms of hypothyroidism to return. Do not stop taking levothyroxine without consulting with your doctor first. If you experience any side effects or have concerns about the medication, discuss them with your doctor before making any changes to your treatment plan.

Is Levothyroxine Safe for Long-Term Use?

Levothyroxine is generally considered safe for long-term use, as long as it is taken as prescribed by a doctor. However, regular check-ups and monitoring of thyroid hormone levels are necessary to ensure the medication is working effectively and not causing any adverse effects.

It is important to always follow up with your doctor if you have any concerns or experience any new symptoms while taking levothyroxine. Additionally, it is important to have your medication refilled on time and not miss any doses to maintain proper thyroid hormone levels.

Overall, with proper usage and monitoring, levothyroxine can be a safe and effective treatment for hypothyroidism.

Interactions

Levothyroxine may interact with other medications, supplements, or foods. Some important interactions to be aware of include:

  • Antacids containing aluminum or calcium can decrease the absorption of levothyroxine.

  • Iron and calcium supplements should be taken at least four hours before or after taking levothyroxine.

  • Certain cholesterol-lowering drugs, such as cholestyramine and colestipol, may also decrease the absorption of levothyroxine.

It is important to inform your doctor about all the medications and supplements you are taking to avoid potential interactions.

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Overdose Potential

Taking too much levothyroxine can lead to an overdose, which can be life-threatening. If you or someone you know shows signs of an overdose (rapid heartbeat, chest pain, difficulty breathing), seek medical help immediately.

Certain individuals may be at a higher risk of experiencing an overdose, such as those with heart disease or who are elderly. It is important to closely monitor your dosage and any changes in symptoms while taking levothyroxine.

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Is Levothyroxine Addictive?

Levothyroxine does not act like addictive drugs do. It does not produce euphoria or pleasure, and it does not cause cravings or withdrawal symptoms when stopped. Long-term use of levothyroxine is not associated with any risk of addiction or abuse.

However, taking too much of the medication can lead to symptoms of hyperthyroidism, which can be dangerous.

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FAQ

Frequently Asked Questions

Some medications may interact with levothyroxine, so it is important to inform your doctor about all the medications and supplements you are taking. Your doctor will determine if there are any potential interactions and adjust your dosage accordingly.

Certain foods, such as high-fiber foods or soy products, may also interfere with the absorption of levothyroxine. It is best to take the medication on an empty stomach for at least 30 minutes before eating breakfast.

Your doctor will determine the frequency of blood tests based on your individual needs, but typically it is recommended to have levels checked every 6-12 months.

It is generally safe to take levothyroxine during pregnancy, as maintaining proper thyroid hormone levels is important for both the mother and baby. However, dosage adjustments may be necessary during pregnancy and after giving birth. Consult with your doctor if you are pregnant or planning to become pregnant while taking levothyroxine.

Levothyroxine can affect blood sugar levels in individuals with diabetes, so close monitoring is necessary. Dosage adjustments may be needed if there are changes in blood sugar levels while taking levothyroxine.