Drug and Alcohol - Medication-Assisted Treatment - Mental Health
Is Trazodone a Controlled Substance?

Wondering, is trazodone a controlled substance? In this essential guide, learn about its classification, uses, and role in recovery and mental wellness.
If you or someone you love is struggling with mental health challenges or addiction, you may have questions about medications like trazodone.
A common concern has been, is trazodone a controlled substance? Trazodone is often prescribed to help with depression and sleep disorders, but understanding its classification and potential risks is essential for those in recovery.
At The Edge Treatment Center, we provide clear, compassionate information to support your journey toward healing. In this guide, we’ll explore trazodone’s role in treatment and whether it poses any concerns for addiction recovery.
What Is Trazodone?
Trazodone is a prescription medication primarily used as an antidepressant. It belongs to a class of drugs known as serotonin modulators, which work by increasing serotonin levels in the brain. Serotonin is a neurotransmitter responsible for regulating mood, emotions, and sleep.
Initially approved by the FDA for the treatment of major depressive disorder (MDD), trazodone is commonly prescribed to individuals struggling with depression. However, due to its sedative effects, it is also frequently used as a sleep aid, particularly for those experiencing insomnia related to anxiety or depression.
Beyond depression and insomnia, some healthcare providers may prescribe trazodone for conditions such as anxiety disorders, post-traumatic stress disorder (PTSD), and chronic pain syndromes.
While it is generally considered safe when taken as directed, understanding its effects and potential risks is crucial, especially for individuals in recovery from substance use disorders.
Is Trazodone a Controlled Substance?
No, trazodone is not classified as a controlled substance by the U.S. Drug Enforcement Administration (DEA) or the Food and Drug Administration (FDA). This means it is not considered to have a high potential for abuse, addiction, or dependence compared to drugs that are classified under the Controlled Substances Act (such as opioids, benzodiazepines, or stimulants).
Trazodone is primarily prescribed as an antidepressant and sleep aid, and while it does have sedative effects, it lacks the chemical properties that typically lead to substance abuse. Controlled substances are classified based on their risk of addiction and dependence, and trazodone does not meet these criteria.
One of the main reasons trazodone is not classified as a controlled substance is its mechanism of action. Unlike opioids or benzodiazepines, which directly affect the brain's reward system, trazodone works by modulating serotonin levels to improve mood and sleep.
While some individuals may misuse it for its sedative properties, the overall risk of abuse is considered low, making it a safer option for those in recovery compared to other sleep aids or anxiety medications.
Potential for Misuse and Dependence

While trazodone is not a controlled substance, it is still possible for some individuals to misuse it, particularly for its sedative effects.
According to the Gateway Foundation, trazodone has been misused in some cases to induce drowsiness or enhance the effects of other substances.
This misuse is more common among individuals struggling with substance use disorders or those seeking an alternative to more potent sedatives like benzodiazepines.
Physical Dependence Vs. Addiction
It is essential to distinguish between physical dependence and addiction when discussing trazodone use:
Physical Dependence occurs when the body adapts to a medication, leading to withdrawal symptoms if the drug is stopped abruptly. This can happen with long-term trazodone use, but it does not mean a person is addicted.
Addiction involves compulsive drug-seeking behavior, loss of control over usage, and continued use despite negative consequences. Since trazodone does not produce euphoria or cravings like addictive substances, the risk of addiction is considered very low.
Minimizing Risks: Proper Usage Matters
To reduce the risk of dependence or misuse, it is essential to:
Follow prescribed dosages—taking more than recommended increases the likelihood of side effects.
Avoid combining trazodone with other depressants like alcohol or opioids, as this can lead to dangerous sedation or respiratory issues.
Taper off gradually under medical supervision rather than stopping abruptly to prevent withdrawal symptoms such as dizziness, nausea, or irritability.

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Side Effects and Withdrawal Symptoms
Like any medication, trazodone can cause side effects, especially when first starting treatment or adjusting the dosage.
While most people tolerate it well, some may experience mild to moderate side effects, and stopping the medication suddenly can lead to withdrawal symptoms.
Common Side Effects of Trazodone

Trazodone is generally well-tolerated, but some common side effects may include:
Drowsiness or fatigue
Dizziness or lightheadedness
Dry mouth
Blurred vision
Nausea or upset stomach
Headaches
These side effects are usually temporary and may improve as the body adjusts to the medication.
However, in rare cases, trazodone can cause more serious side effects, such as irregular heartbeat, severe dizziness, or priapism (a prolonged and painful erection in men), which require immediate medical attention.
Trazodone Withdrawal Symptoms
Although trazodone is not considered addictive, stopping it suddenly—especially after long-term use—can lead to withdrawal symptoms, such as:
Anxiety or agitation
Dizziness or headaches
Nausea or vomiting
Insomnia or vivid dreams
Irritability or mood swings
These symptoms occur because the brain needs time to adjust to the changes in serotonin levels after discontinuing the medication.
Safe Tapering: How to Stop Trazodone Safely
To avoid withdrawal symptoms, it’s important to taper off trazodone gradually under medical supervision. A doctor may recommend:
Reducing the dosage slowly over weeks or months, depending on how long the medication has been used.
Monitoring for withdrawal symptoms and adjusting the tapering schedule as needed.
Consider alternative treatments if trazodone was prescribed for depression, anxiety, or sleep issues.
For individuals in recovery, sudden medication changes can be challenging, so consulting a healthcare provider before stopping trazodone is crucial to maintaining mental stability and overall well-being.
Trazodone in the Context of Recovery
For individuals recovering from substance use disorders (SUDs), finding safe and effective medications to manage depression, anxiety, and sleep disturbances is crucial.
Trazodone is often considered a lower-risk option compared to other medications, such as benzodiazepines or opioids, which have a high potential for abuse. However, it’s crucial to weigh the benefits and risks when prescribing trazodone to those in recovery.
Can Trazodone Be Used Safely in Recovery?
Trazodone is not classified as a controlled substance, and its potential for addiction is low. This makes it a possible choice for individuals in recovery who need support for depression or insomnia. Unlike drugs that directly stimulate the brain’s reward system, trazodone modulates serotonin levels, reducing the likelihood of psychological dependence.
However, some individuals may misuse trazodone for its sedative effects, especially if they have a history of substance misuse. While the risk is lower than with other sedatives, overuse or combining trazodone with alcohol or other depressants can be dangerous.
Benefits and Risks of Trazodone for Those in Recovery
Non-addictive alternative to benzodiazepines for sleep and anxiety.
It helps manage depression, a common relapse trigger.
It can improve sleep patterns, which is vital for long-term recovery.
Potential Risks:
Sedative effects may lead to misuse in some individuals.
It can cause drowsiness or dizziness, impacting daily functioning.
Possible interactions with other medications used in recovery, such as Suboxone or methadone.
The Importance of Personalized Treatment and Monitoring
At The Edge Treatment Center, we emphasize personalized care for every individual in recovery. If trazodone is part of a treatment plan, it should be:
Prescribed with caution, considering the person’s history of substance use.
Closely monitored by a healthcare provider for any signs of misuse or side effects.
Used as part of a comprehensive recovery plan, including therapy and healthy lifestyle changes.
For those in recovery, medications like trazodone can be a helpful tool, but they should always be used under medical supervision to support lasting mental wellness and sobriety.

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Questions About Trazodone and Recovery? We’re Here to Help
Is trazodone a controlled substance? Trazodone is not a controlled substance, but understanding its role in recovery is essential. While it can be a helpful medication for depression and insomnia, it should be used with medical supervision, especially for those with a history of substance use.
If you or a loved one are struggling with addiction or mental health challenges, The Edge Treatment Center is here to help. Our compassionate team provides personalized treatment plans to support lasting recovery. You don’t have to face this alone—reach out today and take the first step toward a healthier, addiction-free life.

We’re Here To Help You Find Your Way
If you or a loved one is struggling with addiction, there is hope. Our team can guide you on your journey to recovery. Call us today.
Written by

The Edge Treatment Center
Reviewed by

Chief Clinical Officer
Drug and Alcohol
Medication-Assisted Treatment
Mental Health
March 16, 2025
FAQ
Frequently Asked Questions
No, trazodone is not a controlled substance. It has a low potential for abuse and addiction, unlike opioids or benzodiazepines. However, it should still be taken as prescribed to avoid misuse or unwanted side effects, especially in individuals recovering from substance use disorders.
Although trazodone is not classified as addictive, some people misuse it for its sedative effects. Taking higher doses or combining it with alcohol or other depressants can be dangerous, leading to excessive drowsiness, dizziness, or even respiratory issues in severe cases.
Trazodone may cause dizziness, dry mouth, nausea, headaches, or blurred vision. Most side effects are mild and improve over time. However, serious side effects, such as irregular heartbeat or prolonged erections in men, require immediate medical attention.
No, stopping trazodone suddenly can cause withdrawal symptoms like dizziness, nausea, irritability, and insomnia. To prevent discomfort, it’s best to taper off the medication gradually under medical supervision, allowing your body to adjust to lower doses safely.
Yes, trazodone is often considered safe for individuals in recovery due to its low abuse potential. However, it should be used under medical supervision to ensure proper dosage and avoid any risk of misuse, especially if the person has a history of substance abuse.